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Table 4 Multiple comparisons of subgroups: postoperative bone level Adjusted p values multiple comparison Control group bone level < 4 mm Control group bone level > 4 mm 0.0453 Control group bone level > 4 mm Perforation group bone level < 4 mm 0.3174 0.7586 Study group bone level < 4 mm Perforation group bone level > 4 mm 0.0203 0.0203 0.0203.
We were unable to uncover substantial interaction effects that would survive multiple comparison control.
For example, GISTIC provides multiple comparison control across markers via Benjamini Hochberg FDR control, which is generally conservative under positive dependence structures (Benjamini and Yekutieli, 2001).
An approximate "heritability" was computed as the portion of variation attributable to strain, which was determined using the partial R. Statistical tests involving each metabolite were treated as separate hypotheses of independent interest and, thus, not subjected to multiple comparison control.
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While the traditional approach to multiple comparisons controls the family-wise error rate, the chance of any false positives, another perspective has recently been introduced.
To establish the significance of the observed regulation for each gene, we used a one sample t-test and corrected the p-value for multiple comparisons controlling the false discovery rate [ 27].
Bonferroni pairwise multiple comparison (with control 0 nM T3) post hoc tests were used to assess differences between individual groups.
Means and standard deviations were calculated from the data obtained and subjected to one-way analysis of variance (ANOVA) followed by Dunnett's post-hoc test for multiple comparison with control.
Individual treatments were tested against the control by using Dunnett's multiple comparison test to control the Type I experimental wise error.
Greenhouse-Geisser-adjusted p values for the analysis of multiple measures and Bonferroni-corrected p values for the multiple comparisons to control for alpha error inflation are reported.
The supporting data analyses were conservatively corrected for the effects of multiple comparisons to control possible Type I error.
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