Sentence examples for multiple common variants from inspiring English sources

Dubois, P.C.A. et al. Multiple common variants for celiac disease influencing immune gene expression.

As with many other complex diseases, risk of developing MS is driven by multiple common variants whose biological effects are not immediately clear.

31 Therefore, it should be examined whether multiple common variants may underpin increased resistance to resective epilepsy surgery.

According to the hypothesis of 'common disease, common variant', common diseases are polygenic diseases manipulated by multiple common variants embedded in coding or regulatory regions.

Our data therefore suggest that multiple common variants within the SLC22A12 locus contribute to the risk of gout, in a population-dependent manner.

It was also found that the predisposition to Barrett's oesophagus was made up of multiple common variants of small effect, rather than a single genetic driver.

For gene fragments without any SNP with MAF less than 5%, the multiple common variant test was carried out.

In the current study, one multiple common variant test and three pooled rare variant tests were examined to determine the significance of the gene fragments and compare the performance of these tests.

Likelihood ratio (LR) tests were conducted for all individual methods for single SNP, multiple common variant, sum test, weighted sum test, function-aided sum test, and combined multivariate pooled test.

Our data suggest that multiple common WNK1 variants, with relatively weak effects, and multiple rare variants with large effects may be associated with blood pressure variation, and this should be explored further.

One is the common variant hypothesis that attributes schizophrenia to the joint effect of multiple common genetic variants, with each contributing a small-to-modest risk of schizophrenia [26].