Whereas our work provides evidence that a synthesis and interaction exist among the three intrinsically coupled networks19 in both brain function and structure, which are systematically engaged during cognition and impact multiple cognitive domains.
Far from adhering to or rejecting these hypotheses, we call upon a more balanced method to consider the brain basis of language and cognition as interplay between multiple cognitive domains.
Many of these theories invoke mechanisms that have the potential to affect multiple cognitive domains, in addition to memory.
Spreng, R. N., Wojtowicz, M. & Grady, C. L. Reliable differences in brain activity between young and old adults: a quantitative meta-analysis across multiple cognitive domains.
Our study provides evidence that the administered multimodal training protocol significantly enhances learning across multiple cognitive domains, spanning executive functions, working memory, and planning and problem solving.
Grady, C. L. et al. A Multivariate Analysis of Age-Related Differences in Default Mode and Task-Positive Networks across Multiple Cognitive Domains.
Grady, C. L. et al. A multivariate analysis of age-related differences in default mode and task-positive networks across multiple cognitive domains.
Third, our results indicate that structural features are more spatially consistent and replicable across multiple cognitive domains, while functional maps may better differentiate cognitive domains.
The temporal lobe has been implicated in multiple cognitive domains through lesion studies as well as cognitive neuroimaging research.
All above results suggest that these extracted ROIs may have pivotal roles as neurocognitive substrates, i.e., so-called neuromarker signatures, as they are common core brain networks among multiple cognitive domains, and are widely impaired in mental disorders50.
Administration of atypical antipsychotic medication enhanced performance significantly across multiple cognitive domains assessed in patients with SC relative to their performance when receiving placebo during a period of antipsychotic withdrawal (3 4 weeks).
