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RCluster randomly grows multiple clusters at the same time, avoiding the greedy agglomerative process implemented in UVcluster.
We did occasionally see multiple clusters at these positions, consistent with fluorescence results in cells overexpressing these proteins.
This explains why some genes are expressed in multiple clusters at the same stage, and why some genes appear in clusters for different expression domains between developmental stages.
6, 7 In terms of the above shortcomings, biclustering is more effective than conventional clustering, since it can cluster both genes and conditions simultaneously, and a gene (or a condition) can be involved in multiple clusters at a time.
We chose a fuzzy clustering method to investigate molecular differences among our TN cohort because it keeps the possibility for each patient to belong to multiple clusters at the same time but with different "degrees of membership".
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The percentage of fibers with multiple clusters (65% at E16, and 75% at E18) in γ/ε-fc mice is significantly higher than in ChAT−/− mice (50% at E17) [14].
An alternative approach was proposed in [67], where an additional Level 3 (L3) controller was used to manage multiple clusters operating at seconds (L1), minutes (L2) and days (L3) intervals.
Notice that, in RCluster, and differently from what occurs in UVCluster, multiple clusters grow at the same time.
In several instances, we have proposed that multiple clusters mapping at fairly close distances and containing individual QTL for which CI essentially overlapped and with the condition that their individual additivity agreed, be coalesced and collectively referred-to as candidate "meta-clusters" (Table 5 and see comments in Additional file 6, Table S4).
"What exactly was going on here?" Further observations by lead researcher Cheng-Jiun Ma provided the critical clue: The temperatures of the constituent gas clouds--whose collective mass far outweighs the galaxies--suggested that the researchers were looking at multiple clusters colliding.
Compared with women who had only one cluster of microcalcifications, the RR of malignancy for women with multiple clusters was significantly raised at 1.25.
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