Multiple clinical testing proved this basic premise correct.
The studies described herein were designed to test the analytical validity of decentralized use of the Prosigna assay across multiple clinical testing sites, following established guidelines [ 25].
The analytical performance of NanoString's Prosigna assay has been validated using FFPE breast tumor specimens across multiple clinical testing laboratories.
All patients in whom SARS was suspected had multiple clinical specimens tested by culture and PCR for SARS-CoV, including nasal swabs, nasopharyngeal swabs, throat swabs, sputum/endotracheal secretions, conjunctival swabs, stool, urine and, if available, bronchoalveolar lavage and post-mortem lung and other tissue samples.
One phenothiazine, methylene blue (MB; phenothiazine methylthionium chloride), has been involved in multiple clinical trials testing its efficacy for many diseases ranging from psychiatric disorders to cancer [ 44].
Multiple clinical trials have tested doublets, triplets and sequential chemotherapy in what is often regarded as a futile attempt to break through this ceiling.
Multiple clinical trials have tested the ability of IFNα to restrict HIV-1 replication or slow disease progression [2], [3], [4], [5], [6].
Multiple clinical outcomes will be tested for their association with CAT scores via multiple ordinary least squares (OLS) regression models.
For CDS tools being used to integrate multiple clinical variables and genetic test results, clinical supporting documentation for the decision options should be transparent to the user to ensure that the scientific basis for the recommended actions are suitable for the patient of interest.
Here, we present results on seven out of 25 analytical validation studies performed on over 200 clinical FFPET specimens as well as external reproducibility study of the test run at multiple clinical sites.
