Multiple Sclerosis has two clinical phases reflecting distinct but inter-related pathological processes: focal inflammation drives the relapse-remitting stage and neurodegeneration represents the principal substrate of secondary progression.
In the majority of patients multiple sclerosis has two clinical phases reflecting distinct but inter-related pathological processes: focal inflammation drives activity during the relapse-remitting (RR) stage and neuroaxonal degeneration represents the principal substrate of secondary progression (SP), a stage that has few if any relapses.
To examine potential confounding, we repeated the analyses with multiple clinical characteristics at each phase added as covariates in the model.
Multiple VLPs are currently evaluated in clinical phases requiring a straightforward and rational process design.
It is currently being evaluated in multiple clinical trials (as TRC102, TRACON Pharmaceuticals, Inc., San Diego, CA, USA) and has completed phase-I testing in combination with pemetrexed.
Schuld et al. sought stronger evidence by using multiple clinical settings with large patient populations and examining cyclic phenomena (e.g. weather, lunar phase, and season) [ 19].
N-acetylcysteine: multiple clinical applications.
Multiple clinical testing proved this basic premise correct.
15 A PD-L1 IHC assay has been used to determine PD-L1 expression in a clinical phase 1 multiple dose escalation study of nivolumab in patients with previously treated advanced melanoma, NSCLC, RCC, CRPC, or CRC [Bristol-Myers SquiBMSInc. (BMS)/Dako presentation, 2013 World Conference on Lung Cancer, online publication].
One-way ANOVAs were used to statistically analyse the difference among the CML clinical phase patients, and the multiple treatments for cells.
