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However, even a limited number of markers give rise to many testable genotype-outcome associations, when the markers are combined with each other and with multiple clinical outcome parameters and patient subgroups.
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Two prospective studies measuring multiple clinical outcomes are currently underway.
Multiple clinical outcomes were analyzed using standardized procedures, which provided a comprehensive look at the ABCs.
Multiple clinical outcomes were assessed using standardized procedures, which allowed us to better characterize diabetes control.
Multiple clinical outcomes will be tested for their association with CAT scores via multiple ordinary least squares (OLS) regression models.
A randomized trial to evaluate alcohol consumption and risk of multiple clinical outcomes with sufficient power to evaluate prespecified genetic environmental interactions would be ideal.
Participants' preferences for risk displays about multiple clinical outcomes were elicited by asking participants to choose between 2 sets of 3 graphs.
For our second primary outcome of improvements in global disease control, we will employ a multivariate model that jointly tests the changes in multiple clinical outcomes, namely A1c, LDL cholesterol and systolic blood pressure [ 29].
A novel approach that has been recently incorporated into the design of cardiovascular clinical trials is to examine multiple clinical outcomes for evidence of a drug's activity and worthiness for further evaluation.
Baseline patient demographics, injury severity, fluid and blood product resuscitation parameters, serial laboratory values and multiple clinical outcomes, including complicated recovery and 28-day mortality, were obtained from the TRDB.
In fact, sedation protocols that use validated sedation scales [ 59], emphasizing intermittent boluses rather than continuous infusions [ 43], and promoting daily interruption of sedatives and analgesics [ 60] significantly improve multiple clinical outcomes.
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