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This result further suggests that PTEN protein sequence contains multiple cleavage sites.
In any event, our overall result is clear: falcipain-2 and falcipain-3 are capable of rapid hydrolysis of hemoglobin at multiple cleavage sites.
Such utilities include multiplexing for inducing multiple cleavage events, controlling gene expression, and site specific transgene insertion.
The cleavage results in double-stranded duplexes.
Multiple cleavage sites were identified for both falcipains (Fig. 2a d, top arrows).
Kindler syndrome, a mixed type, exhibits multiple cleavage planes.
Both alkali- and RecA*-mediated cleavage screens yielded similar cleavage results, with the exception of position P5, where RecA*-mediated cleavage was more restrictive than alkali-mediated cleavage.
During the maturation process, multiple cleavage events including CA-SP1 sequentially take place.
Multiple cleavage sites that were associated to the same poly(A) signal were omitted.
The doublet seen with fractin may represent multiple cleavage products created by caspase-3.
Interestingly, we also identified multiple cleavage sites within 16S, 23S and 5S rRNA.
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