Sentence examples for multiple cleavage events from inspiring English sources

Such utilities include multiplexing for inducing multiple cleavage events, controlling gene expression, and site specific transgene insertion.

Since pre-miRNA processing requires only a single DCR-1 cleavage event, one possibility is that RDE-4 increases the affinity of DCR-1 for long dsRNA so that multiple cleavage events can occur before the enzyme dissociates.

During the maturation process, multiple cleavage events including CA-SP1 sequentially take place.

Fragment ions that are consistent with ones evolving from multiple cleavage events are listed next to each of the contributing cleavage sites.

Thus, multiple cleavage events within the lung and here particularly in endothelial cells contribute to the regulation of vascular permeability and neutrophil transmigration in vitro and in vivo, and therefore no single ADAM17 substrate can be held responsible for this process.

Base-pairing interactions between the pre-rRNA and its complementary regions in U3 snoRNA guide, by a complex and incompletely understood mechanism that includes the participation of U14 [ 27, 28] and U17/snR30 [ 29- 31] snoRNAs, the multiple sequence-specific pre-rRNA cleavage events that eventually liberate the mature 5'-end of the 18S rRNA [ 22- 26, 32].

Certain other toxin proteins have an array of repeats of the caspase-like domain upstream of the C-terminal toxin domain (e.g. a protein from Streptomyces flavogriseus with ADP-ribosyltransferase and MCF peptidase toxin domains; gi: 357410654; see below), suggesting that their processing might involve multiple autoproteolytic events to release multiple cleavage products.

To distinguish if these were the result of multiple rounds of flap creation and cleavage or whether they represent single flap cleavage events with a broad size distribution, we measured initial flap cleavage products (CPs) by labelling the downstream Okazaki fragment at the 5′ end and performing maturation assays as before.

It has been shown that miRNAs are incorporated into multiple-turnover enzymes such that a single microRNA can guide several consecutive cleavage events [ 30].

This result further suggests that PTEN protein sequence contains multiple cleavage sites.

In any event, our overall result is clear: falcipain-2 and falcipain-3 are capable of rapid hydrolysis of hemoglobin at multiple cleavage sites.