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Based on these values, multiple chromosomes are unlikely to receive a crossover during meiosis in mlh3 Δ mms4 Δ.
Elements that span matching blocks of different chains and elements that map to multiple chromosomes are filtered out.
Therefore, we further tested whether the predicted dif sites in multiple chromosomes are all located near the GC skew shift-points.
A junction is defined as a boundary point of genome blocks on chromosomes where two distinct ancestral origins meet, and the boundary points that occur at the same location along multiple chromosomes are counted as a single junction.
Besides the γ-Proteobacteria, to which the Vibrionaceae belong, complete genome sequences composed of multiple chromosomes are available for the α-Proteobacteria (Rhizobiaceae, Brucellaceae and Rhodobacteraceae families), the β-Proteobacteria (Burkholderiaceae and Comamonadaceae families), the Chloroflexi (Sphaerobacteraceae), the Deinococci (Deinococcaceae) and the Spirochaetes (Leptospiraceae).
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30 bacteria with multiple chromosomes were removed as well.
Several novel genes residing in multiple chromosomes were also found to be highly influential to the three endophenotypes.
Bacterial species with completely sequenced genomes composed of multiple chromosomes were identified through filtered queries on the NCBI Entrez system [ 89].
The problem of optimizing multiple chromosomes is converted to the problem of finding a cycle on this graph.
Some chromosomes were observed to be excluded from nucleus formation at telophase II, and multiple chromosomes were often observed as laggards at anaphase II.
Hence, our analysis provides sound support to the hypothesis that the genomic distribution of primary regulons in species with multiple chromosomes is predominantly skewed towards the large chromosome.
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