Sentence examples for multiple chimeric transcripts from inspiring English sources

Multiple chimeric transcripts translate to proteins of 190 or 210 kd and, rarely, 230 kd.

Even using multiple methods for detecting chimeric transcripts, we estimate that only 0.46% of protein coding genes in Drosophila generate chimeric transcripts.

To detect chimeric transcripts, reads from multiple tissues were aligned to their respective genomes using gsnap (Wu and Nacu 2010) (parameters: -t 30; -B 4; –nofails; -A sam; -m 2; -n 1).

The low number of isotigs with multiple matches indicates a low frequency of chimeric transcripts.

T r,s) is made up of three values: DW r,s) counts reads that represent sequences present only in wild-type transcripts, T1 r,s) counts reads that represent sequences present once in both the wild-type and chimeric transcripts, and T2 r,s) counts reads that represent sequences present once in wild-type transcripts, but multiple times in chimeric transcripts (Additional file 1: Figure S1B).

The unparalleled ability of TEs to generate genetic novelties is reflected in the fact that many of the Pack-MULEs contain sequences from multiple chromosomal loci that are fused to form new open reading frames, some of which are expressed as chimeric transcripts.

Other repetitive elements, such as Pack-MULEs, have been shown to carry fragments of cellular genes from multiple chromosomal loci, some of which can be fused together to form novel open-reading frames that are expressed as chimeric transcripts (Jiang et al. 2004).

Theoretically, all splicing events as well as chimeric transcripts can be directly detected [10].

Consequently, the majority of mRNA chimeric transcripts code for peptides long enough to be assumed functional.

Traditionally, chimeric transcripts have been discarded as artefacts, primarily causing problems in annotation and gene indexing/clustering projects.

For instance, trans-splicing [18] [20], the event of joining the exons of two heterologous transcripts, provides a mechanism for the generation of chimeric transcripts.