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Most other studies reporting rates of neutropenia after IP chemotherapy included treatment with multiple chemotherapy agents with varying toxicity profiles and/or nonhyperthermic IP chemoperfusions.
Designing a composite predictive score to use in assessing the toxicity of multiple chemotherapy regimens therefore appears to be a valid undertaking.
Table 3 summarises chemotherapy toxicities per patient.
Chemotherapy toxicities were mainly haematologic and well tolerated.
Chemotherapy toxicities were graded according to World Health Organization criteria (World Health Organization, 1979).
Additionally, severe chemotherapy toxicity may result in participants feeling too unwell to complete PROs.
Nevertheless, during PRRT as well as chemotherapy, toxicity is an aspect of great concern.
How can these patients be identified to spare chemotherapy toxicity?
Four patients showed chemotherapy toxicity, and chemotherapy was ceased before the first-treatment response evaluation.
Chemotherapy toxicity was recorded for a total of 115 courses of chemotherapy in 27 patients.
These data include a combination of multiple toxicity phenotypes, such as liver toxicity and kidney toxicity.
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