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These women were 18 times more likely than control subjects to suffer from multiple chemical intolerances.
Although both women and men report multiple chemical intolerances, several studies suggest that many more women than men may be affected.
Likewise, women with the so-called rapid-acetylator form of NAT2 were four times more likely to report multiple chemical intolerances.
The study, reported in the October 2004 International Journal of Epidemiology, investigated for the first time genetic differences between women reporting multiple chemical intolerances and those without such intolerances.
People who suffer from multiple chemical intolerances, a condition sometimes referred to as "multiple chemical sensitivity," report wide-ranging symptoms such as headaches, short-term memory problems, confusion, fatigue, depression, irritability, and breathing difficulties.
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They identified multiple chemical intolerance sufferers using criteria derived from earlier studies, including one by James R. Nethercott and colleagues in the January/February 1993 Archives of Environmental Health, which defines cases as those with symptoms that are chronic, that are linked to a low level of exposure to chemical agents, and that resolve with removal of the exposure.
A comprehensive term for chemical intolerance is "multiple chemical sensitivity" (MCS), which is associated with symptoms in more than one organ after the sufferer has been exposed to very low concentrations of chemical substances (Cullen 1987).
Owing to similarities with other (unproven) environmental intolerances, such as multiple chemical sensitivities, and because scientific evidence of a causal relationship between EMF exposure and symptoms is lacking, the WHO introduced the broader term Idiopathic Environmental Intolerance (IEI). 1 When afflicted persons attribute their illness to EMF, it is referred to as IEI-EMF.
Idiopathic environmental intolerance (IEI), also known as multiple chemical sensitivity, is a clinical description for a cluster of symptoms of unknown etiology that have been attributed by patients to multiple environmental exposures when other medical explanations have been excluded.
Multiple chemical sensitivities (MCS) syndrome, also known as idiopathic environmental intolerance, is a controversial diagnosis that encompasses a wide range of waxing and waning, subjective symptoms referable to more than one body system and provoked by exposure to low levels of chemicals, foods, or other agents in the environment.
Hypersensitivity against common environmental chemicals belongs to a complex of symptoms which are frequently reported by individuals suffering from a condition, variously referred to as multiple chemical sensitivity (MCS), chronic fatigue syndrome (CFS), or idiopathic environmental intolerance (IEI).
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