Sentence examples for multiple changes including from inspiring English sources

This method is in principle compatible with any circular vector that can be propagated with a dam+ E. coli host to generate protein variant library with multiple changes, including mutation, short sequence deletion and insertion, or any mix of them.

The transition from the restrained and controlled growth of normal cells to the accelerated and dysregulated growth of cancer cells requires multiple changes, including enhancement of the signaling pathways controlling division and survival.

The study was undertaken after an unexplained increase in SSI, following a period of multiple changes, including the implementation of fast-track surgery.

Passing on a 6-0 vote, with Councilman Joe Carchio absent, the multiple changes include tweaks to operating hours and outcall massages, occasions when the therapist travels to the client.

Although multiple mutations in noncontiguous chromosomal loci of H37Ra collectively lead to multiple phenotypic changes including virulence attenuation, it is likely that one or two initial mutations affecting global metabolic regulation might provide some advantage for in vitro survival under the conditions of aging and cell lysis (Figure 5).

The French soprano Emmanuelle de Negri delivered a haunting, long-breathed "Plaint," and the British tenor Ed Lyon maintained a sweet, crisp voice through multiple costume changes (including nothing more than a fig leaf in the final masque).

Thereafter the band experienced more moderate success while undergoing multiple personnel changes (including Green's departure and the addition of McVie's wife, keyboardist-vocalist-songwriter Christine).

Research shows that hormone levels affected "multiple physiological changes, including increased cortisol and … impaired metabolism" when sleep was disrupted as a result of subjects only receiving four hours per night.

Colorectal cancer arises through multiple genetic changes, including mutations of APC, TP53, RAS, and RAF (Kouzminova et al, 2010).

Atrial fibrillation (AF) is the most common arrhythmia, especially among elderly populations, and is the end-stage manifestation of multiple pathological changes, including both structural and electrical remodelling.

In contrast to CKD, impaired GFR in CHF seems to be predominantly due to multiple haemodynamic changes (including impaired perfusion or/and venous congestion).