Sentence examples for multiple centres to from inspiring English sources

Research into this field should concentrate on longitudinal design, with pooling of data from multiple centres to achieve larger cohorts.

This is due to different factors, such as the small number of BRCA mutation carriers, which necessitate multiple centres to participate.

Clearly, further prospective work is required across multiple centres to standardise the reporting of BVI, an important determinant of outcome in primary operable ductal breast cancer.

Further studies are required to determine the likely level of intervention in the standard care arm in multiple centres, to develop additional placental biomarkers and to confirm that the composite outcome is valid.

Further work is required to determine the likely level of intervention in the standard care arm in multiple centres, to develop additional placental biomarkers and to confirm that the composite outcome is valid.

Ideally, these measurements should be formulated into a standardized protocol that can be applied at multiple centres, to permit sufficiently large numbers of samples for meaningful analysis to be collected.

Qualification, defined as a "graded, fit-for-purpose evidentiary process linking a biomarker with biological processes and clinical end-points", is a validation process in large cohorts of patients involving multiple centres, similar to phase III clinical trials, to obtain regulatory approval as surrogate endpoints [4].

Multiple centres elected to use immunomodulator drugs instead of low-dose steroids for maintenance therapy (n=5).

Besides some of the proteins found to be differentially abundant in this disorder may be candidate biomarkers for disease diagnosis and prognosis for which validation studies in individual patients in larger populations across multiple centres need to be carried out.

From an operational perspective, attention is a matter of organizing multiple brain centres to act in concert on the task at hand.

The present phase II study was conducted at multiple Asian centres to evaluate the tolerability and efficacy of bevacizumab plus capecitabine in patients with advanced or metastatic HCC.