Sentence examples for multiple cellular signaling from inspiring English sources

Cancer cells exhibit deregulation in multiple cellular signaling pathways.

Also, flavonoids are found to have an effect on several mammalian enzymes like protein kinases that regulate multiple cell signaling pathways and alterations in multiple cellular signaling pathways are frequently found in many diseases.

However, the fact that the primary cilium is now understood to be a central coordinator for multiple cellular signaling pathways has complicated our mechanistic understanding of cystogenesis and has offered diverse and sometimes contradictory paths to therapeutic designs.

Emerging evidence has shown that some "natural products" such as isoflavones, indole-3-carbinol (I3C) and its in vivo dimeric product 3,3′-diindolylmethane (DIM), and curcumin among many others, have growth inhibitory and apoptosis inducing effects on human and animal cancer cells mediated by targeting multiple cellular signaling pathways in vitro without causing unwanted toxicity in normal cells.

The serine/threonine protein phosphatase 5 (PP5) regulates multiple cellular signaling networks.

It is well known that in all cancer stages from early to advanced disease, cancer cells are known to have alterations in multiple cellular signaling pathways drives normal cell to carcinoma (Wu et al. 2009).

However, the act of simply inhibiting or activating GSK-3 is expected to bring about undesirable side effects given that GSK-3 is associated with multiple cellular signals.

Effective treatment of arthritic conditions will benefit from a strategy that can simultaneously target multiple cellular signalling pathways to effectively downregulate inflammation in chondrocytes without adverse systemic effects.

Binding of AGEs to RAGE induces activation of multiple cellular signal transduction pathways, including activation of p21ras pathway and a cascade of MAPK (Schmidt et al. 1995, 1999).

Furthermore, each miRNA is capable of regulating the expression of many genes, allowing them to simultaneously regulate multiple cellular signalling pathways.

Together with other recent studies, our work reveals that multiple cellular signals can trigger assembly of a variety of actin structures in the nucleus, each with a unique morphology, function, and regulatory mechanism.