Sentence examples for multiple cellular models from inspiring English sources

In multiple cellular models, induction of c-Myc expression correlated with induction of the mir-17 cluster.

Yet, dacarbazine has been studied in multiple cellular models of melanoma, and the consistent observation is that dacarbazine promotes a relatively weak apoptotic response.

Models of cardiac tissue have therefore been constructed to describe the propagation of the AP in 1, 2, and 3 dimensions 39 by linking multiple cellular models in a spatially relevant way.

Collectively, these data show a strong neuroprotective effect of enhanced 14-3-3 14-3-3 14-3-3particularly of thexpression, - ɛ, and - γ isoforms – in multiparticularly and animal mofels of PD, and pointheo 14-3-3 14-3-3 14-3-3of these proteins in the development of neuroprotective therapies for human PD.

We and others have shown that DYRK1A is important for phosphorylation of tau protein on multiple sites in several cellular models [3], [4], [6], [7].

Thus, ganetespib treatment results in sustained inhibition of multiple oncogenic targets in these cellular models of JAK2-driven malignancy.

The method introduced in this work provides the ability to study the system-level effects of combinations of drugs and use the data to select combinations that can lead to desired outcomes by comparing the mathematical models of multiple cellular types.

Cyclooxygenase inhibition suppresses tumour cell growth and invasion, and retards the formation of liver metastasis in a mouse CRC model by multiple cellular and molecular mechanisms.

Previous reports have shown that it is able to suppress proliferation, induce apoptosis, and inhibit invasion, angiogenesis, and metastasis in various cancer types in both in vitro and in vivo models by targeting multiple cellular signalling pathways [ 102, 103].

There were fourteen preclinical studies describing multiple effects of NS in animal or cellular models of asthma including bronchodilation, anti-histaminic, anti-inflammatory, anti-leukotrienes and immunomodulatory effects.

Extensive research in postmortem brain tissue from AD subjects, and AD animal and cellular models revealed that mitochondria undergo multiple malfunctions during the course of this disease.