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All other studies that took peri-operative samples used detection of multiple cellular markers.
Three studies by the same group (Uen et al, 2007, 2008; Wang et al, 2007) used a membrane array technique to detect multiple cellular markers.
Whereas use of multiple cellular markers might be expected to increase sensitivity and specificity, detection rates were found to be similar in each series and across all markers.
Although the use of nanotechnology has generated excitement in the area of tumour biology, especially enabling the simultaneous monitoring of multiple cellular markers based on the tunability of the nanostructures, another application that is achieving major milestones towards clinical applicability is the use of nanoparticles to image tumours in vivo.
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This initial classification was followed by counterstaining experiments with multiple sub-cellular markers.
We have examined the differences in cellular markers and gene expression between multiple macrophage populations from 25 pigs of five breeds.
Tumors, most commonly, tend to be comprised of multiple cellular clones and this fact may alter the marker expression.
Enabled by novel molecular markers, fluorescence microscopy enables the monitoring of multiple cellular functions using live cell assays.
For precise analysis and correct interpretation in vivo, multiple color labeling is required to time-course monitor many cellular markers and signaling molecules at the same time.
Altogether, ultrastructural analysis showed that deletion of the p35 gene caused multiple intracellular changes that resembled the accelerated and enhanced appearance of cellular markers of brain aging, including alterations and perhaps impairment of the autophagy process.
Both phases are complex and require exquisite organization of multiple cellular systems, including interactions between proteins and cellular membranes.
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