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Our laboratory has developed a protein delivery protocol that allows the uptake of exogenous protein that can exert its function in multiple cells including podocytes.
Similar to cell-free reconstitution experiments using fresh cytosols from multiple cells including MDA-MB231, LNCaP, PPC-1, PC3, Du145, NHP, K562, HCT116, and C2F3 (see Materials and Methods for descriptions of cells) also revealed CC-initiated caspase activation without requiring exogenous nucleotides (data not shown) [16].
Multiple cells, including neutrophils and macrophages, express integrins and other receptors that bind fibrin and/or fibrinogen [ 43].
NGF and BDNF are expressed in multiple cells, including epithelial cells, active immune cells, and neural cells.
We show that OGT-dependent apoptosis requires OGT catalytic activity and occurs in multiple cells including an insulinoma cell line, INS-1.
In the case of neurotrophic factors, an additional level of modelling complexity is added by the fact that they are secreted, and will affect multiple cells, including non-transduced ones.
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In contrast, Tanshinone IIA has been shown to repress cell growth through inducing apoptosis in multiple cancer cells, including leukemia cells, osteosarcoma cells, and prostate cancer cells52,53,54.
Artemisinin and ART have been shown to induce cell death in multiple cancer cells, including colon, breast, ovarian, prostate, pancreatic and leukaemia cancer cells.
Stemulate is a GMP grade pooled human platelet lysate, which supports the expansion of multiple types of cells including MSCs.
Cholesterol has multiple effects upon cells, including altering membrane fluidity, protein trafficking, endocytosis, and exocytosis [ 58].
RNAs perform multiple vital roles within cells, including catalyzing biological reactions and expression of proteins.
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