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The AVE has been suggested to comprise multiple cell subpopulations [4], [23].
Together these observations provide strong support for the notion that the AVE is indeed composed of multiple cell subpopulations.
However, it is becoming increasingly clear that the NP comprises multiple cell subpopulations [ 8- 11].
These tumors are comprised of multiple cell subpopulations having a spectrum of proliferative and regenerative capabilities.
Cervical carcinomas generally show significant intratumor heterogeneity in oxygenation [ 6, 7, 13, 14], and oncogenic mutations induced by fluctuating hypoxia or other factors may lead to the development of multiple cell subpopulations [ 16, 26].
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Given that multiple-cell subpopulations are seen across the small tumor cell and small tEC, we sought to better characterize these distributions using mixture modeling.
VEGFR1 and VEGFR2 are assumed to follow a multiple component mixture model, given the multiple-cell subpopulations observed by the data, while only one population is observed in the nonlabeled cell populations, or autofluorescence datasets.
When these small cells and large cells are further analyzed, as a histogram, we observe that both the small tumor cells (Fig. 3C) and small tEC (Fig. 3D) contain multiple-cell subpopulations.
SAIL expression was detected in multiple hematologic cell subpopulations in normal PBMC (n=6) and BMMC (n=5) specimens by flow cytometry analysis.
Multiple stem-cell subpopulations can thus exist in the same organ; since their discovery is often prompted by the use of new markers or combinations of markers, more are likely to be discovered in the future.
Biological processes are often accompanied by occurrences of multiple events, such as activation of certain cell types, change in prevalence of cell subpopulations (such as T cells), changes in concentration of proteins or peptides, or breaks in chromosomes.
More suggestions(15)
multiple ploidy subpopulations
multiple cell chips
multiple cell lineages
multiple cell phones
multiple cell sites
multiple cell compartments
multiple cell lines
multiple cell sheets
multiple cell identifiers
multiple cell layers
multiple cell functions
multiple cell CyPs
multiple cell divisions
multiple tumour subpopulations
multiple cell populations
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