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In addition, this approach provides designers with multiple candidate designs.
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For reverse primers, multiple candidates were designed within highly conserved P2 and P3 regions (Figure 1).
Although this is an elegant approach in general, calculating this distribution requires the evaluation of further integrals and thus becomes rapidly computationally expensive for high-dimensional design spaces, e.g. if multiple candidate measurements are planned within a single experiment.
Figure 3 and Additional file 1: Figure S5 show all candidate designs and Pareto optimal designs for multiple (two and three-dimensional) engineering goals.
(e) Direct deconvolution techniques are very efficient for screening multiple candidate ligands of unknown concentration in a mixture, but the design, preparation and analysis of the chemical tags for coding candidate ligands in each mixture is quite challenging[ 18- 21].
Because the results of the as-yet few and relatively small-scale studies are not wholly consistent, there is a clear need for larger-scale and carefully designed studies that examine multiple polymorphisms of multiple candidate genes.
In this section, we describe the multiple candidate solution for reduction of PAPR. Figure 1 describes the multiple candidate system and our PDF notation for several variables.
Using their particular design and screening strategy, the investigators have identified multiple candidate molecules as potential cough suppressants.
In [11], the design procedure can be visualized as a "top-down" approach where a given bandwidth is divided into multiple candidate subbands based on a predetermined moduli set.
Finally, for the multiple candidate technique is given by (12).
Taking the limit of single candidate target, we consider multiple candidate targets.
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