Sentence examples for multiple candidate biomarkers from inspiring English sources

Advanced MRI applications have generated multiple candidate biomarkers in ALS (8).

This increases the feasibility of assaying large sample numbers with sufficiently high specificity and sensitivity to enable the simultaneous statistical validation of multiple candidate biomarkers [ 57].

In addition, our microscale platform has significantly reduced the number of cells required for each endpoint, ultimately allowing multiple candidate biomarkers to be screened simultaneously with primary cells isolated from small biopsies from patients.

The relatively recent introduction of a multiple reaction monitoring (MRM) mass spectrometry platform for the measurement of peptides has provided the opportunity to develop multiplexed assays for simultaneously measuring multiple candidate biomarkers and to progress them through the biomarker development pipeline [ 65].

This clinical need has led to the development of multiple candidate AKI biomarkers [ 6, 8- 10].

Where there are multiple candidate pharmacologic biomarkers as is the case with tipifarnib, a comprehensive, parallel study of all candidates is required.

In 66 relevant publications, numerous candidate biomarkers from multiple sources were identified.

In addition to albuminuria, multiple investigators are pursuing novel candidate biomarkers that are not currently used in common clinical practice.

They measured several clinical variables, collected fasting serum, and measured many candidate biomarkers from multiple diabetes-associated pathways.

An ultrasensitive immunoassay was used to measure of 58 candidate biomarkers in multiple diabetes-associated pathways, along with six routine clinical variables.

The discrepancy in fold change may be a consequence of the semi-quantitative nature of spectral counting with mass spectrometry, and reflects the need for future validation of other candidate biomarkers, using multiple reaction monitoring (MRM) or ELISA.