c, WRN dependency in multiple cancer types.
Overexpression of the metabolic enzyme BCAT1 has been observed in multiple cancer types.
Collectively, these data suggest that PARP14 may play an oncogenic role in multiple cancer types.
Representative examples of ECDs and LCDs across multiple cancer types are shown in Fig. 5c.
Tibshirani, R., Hastie, T., Narasimhan, B. & Chu, G. Diagnosis of multiple cancer types by shrunken centroids of gene expression.
Thu, K. L. et al. SOX15 and other SOX family members are important mediators of tumorigenesis in multiple cancer types.
This system has been adapted for unbiased screens to identify drivers of multiple cancer types.
We observed overall elevated expression of snoRNAs and their ribonucleoproteins in multiple cancer types.
Highly frequent somatic mutations in genes encoding core cohesin subunits have been reported in multiple cancer types.
Together, these results suggest that the H19/SAHH/DNMT3B axis is active in multiple cancer types, where it can mediate metformin-induced hypermethylation of H19.
We show that predicted miRNA-target associations that retain significance across multiple cancer types involve a number of critical tumour suppressor genes and oncogenes.
