Sentence examples for multiple cancer subtypes from inspiring English sources

The results obtained are found to be promising and can possibly have important impact in the area of unsupervised cancer classification as well as gene marker identification for multiple cancer subtypes.

Multiple international projects, like The Cancer Genome Atlas, were initiated to analyze the genetics of multiple cancer subtypes.

Future, larger studies of multiple cancer subtypes are necessary to help confirm the value of BTL as a universal cancer biomarker.

Moreover, genomic aberrations often affect only a subset of the cancer patients, and multiple cancer subtypes may be present, as in the Mullighan data set.

This indicates that the pan-cancer functional relationships in the addiction patterns carry information beyond the tissue origin alone, which may therefore be more closely connected to the underlying biology shared by multiple cancer subtypes.

It is critical to note that the role of FOXA1, as a tumor oncogene or a tumor suppressor gene, has been reported to vary in prostate and breast cancers depending on multiple cancer subtypes and states of hormone dependence or independence [ 11, 12, 28].

Multiples studies show the importance of Notch signaling in multiple breast cancer subtypes and its role in invasive disease.

Although initially thought to correlate with estrogen receptor (ER) expression, IGF-1R has recently been implicated in multiple breast cancer subtypes and its expression correlates with poor prognoses [9], [10].

Being a central integrator of multiple pathways, activation of HSP90 may maintain the malignant phenotype, facilitate metastasis, and promote treatment-resistance under the stress of cancer therapy in multiple breast cancer subtypes.

Large-scale parallel sequencing has revealed subtype-associated gene mutations as well as a small number of genes that are frequently mutated across multiple breast cancer subtypes such as TP53 and PIK3CA/PTEN [ 14].

Preclinical data suggest that Src inhibitors may be effective as a single agent in basal-like tumours, or a part of a combination therapy with other targeted agents in multiple breast cancer subtypes.