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The presence of multiple CaM isoforms is a defining characteristic of CaMs in plants.
Induced expression of some but not all of the multiple CaM isoforms in a plant tissue in response to certain stimuli has been reported [ 10, 23] thus, competition among CaM isoforms for target proteins may be found.
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The phenomenon of multiple genes encoding identical CaM isoforms has been described in previous studies; Arabidopsis AtCaM2/3/5, N. tabacum NtCaM3/4/5/6/7/8/11/12, rice OsCaM1-1/2/3 OsCaM1-1/2/3aM1/3 all soybeanaM isoforms [ 6- 8, 10].
The multiple CaM genes, which encode identical protein isoforms may be related to similar situations in which there are gene families that encode similar, but not identical proteins, such as those involved in disease resistance (R) [ 28, 29] and encoding GST [ 30].
In 1953 Singer was also developing its Perla Patent as used in its '306' replaceable cam machine and in 1954 its '319' machine-carried multiple cam machine.
The six SlCaM genes encode four CaM isoforms.
In rice, five genes encode three CaM isoforms.
Most CAM users mentioned using multiple CAM modalities, averaging 4.25 ± SD 2.08 modalities per CAM user.
Twenty-eight physicians had multiple CAM certificates.
Thus these five genes encode for two distinct potato CaM isoforms.
Differences between CaM isoforms were observed, suggesting specificity in the response.
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