Your English writing platform
Discover LudwigSuggestions(1)
Exact(1)
Based on these results, the properties of QTL that underlie a trait can explain the limited benefit or the absence of benefit of combining information from multiple breeds that is described in empirical studies as opposed to the substantial benefit that is achieved in simulation studies.
Similar(59)
Understanding the multiple components of functional breed diverstiy have important implications for breed management and genetic improvement practices, especially in breeds that are locally adapted and have not undergone intense artificial selection.
However, because of the way breeding programs operate currently and because relationships contribute significantly to prediction accuracy, in practice, it may not be possible to avoid this problem, other than by using training populations that include multiple breeds or lines.
In a preliminary study, we explored the application of NCD to two sheep populations, one that included multiple breeds [ 7] and another with known sire groups and a half-sib population structure (unpublished data).
Although simulation studies show that combining multiple breeds in one reference population increases accuracy of genomic prediction, this is not always confirmed in empirical studies.
It has been reported that using multiple breeds to predict GEBV can be effective to increase the size of the reference population and in turn increase accuracy of selection [ 29].
It has initiated programs that have saved multiple breeds from extinction, and works closely with similar organizations in other countries, including Rare Breeds Canada.
We used a set of animals that originated from multiple breeds.
As suggested by [ 27], one benefit of adding breeds to the training set is the possibility of identifying SNPs that are in strong linkage disequilibrium with the QTL and with an allelic phase that is preserved across multiple breeds.
So for large QTL that segregate in multiple breeds, there, appears to be more precision in the multi-breed analysis.
SNPs utilized were also selected to have a minimum minor allele frequency and tend to be those that segregrate within multiple breeds [ 30].
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com