Sentence examples for multiple breast cell from inspiring English sources

Here, we further investigated DACT1 expression in multiple breast cell lines and primary tumors, and further studied its function and molecular mechanisms.

Clearly, S100A2 is regulated by BRCA1 at a protein and mRNA level in multiple breast cell lines and in primary breast cancers.

We report that these compounds in combination exert a variable antiproliferative effect across multiple breast cell lines, which is synergistic in SK-BR-3 cells and triggers cell signaling events not predicted by the activity of either compound alone.

Here, we further examined the expression and promoter methylation of DACT1 in multiple breast cell lines and primary tumors, and evaluated its potential as a tumor biomarker for breast cancer.

We observe consistent growth inhibitory effects in multiple breast cancer cell lines and non-tumourigenic breast cell lines, consistent with its role as a tumour suppressor in breast tissue.

In this study, we showed for the first time that pleurocidin-family CAPs NRC-03 and NRC-07 are cytotoxic for multiple breast cancer cell lines, including SKBR3 cells that contain a 100% ALDEFLUOR-positive breast cancer stem cell population [ 34].

We have shown for the first time that the pleurocidin-family CAPs NRC-03 and NRC-07 are cytotoxic for multiple breast cancer cell lines, including MCF7-TX400 cells that overexpress P-glycoprotein, and slow-growing SKBR3 cells that contain a 100% ALDEFLUOR-positive breast cancer stem cell population.

In multiple breast cancer cell lines, DDX21 protein knockdown triggered cell cycle arrest as well as massive cell death and caused a significant reduction in anchorage-independent cell growth in vitro as well as in vivo.

Specifically, the small molecule was found to be cytotoxic against chemoresistant patient-derived primary cells in addition to multiple breast cancer cell lines at low micromolar concentrations.

Here we demonstrate on the basis of a cell viability assessment determined using multiple breast cancer cell lines that 267 in combination docetaxel (Dt) interacted in a synergistic manner (increased therapeutic benefit over single agents as assessed by the median effect methodology developed by Chou and Talalay [ 26]).

Using the 3D culture model, we showed that reducing P4HA2 expression or inhibiting its activity significantly inhibited cell proliferation and suppressed the malignant phenotypes in multiple breast cancer cell lines.