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Stimulation of the topmost layer of the spinal cord, which conveys touch sensations to the brain, may work by disrupting these abnormal oscillations, restoring normal firing patterns across multiple brain structures involved in the control of voluntary movements.
In this work, we report on the fabrication of two types of optrode arrays for in vivo optogenetic applications, including a microwire optrode array for investigating single brain regions and a drivable optrode array for simultaneously targeting multiple brain structures.
5-HT2CRs are widely expressed in multiple brain structures, including the DMH, LHA, and NAc [27], [28].
The thalamus as the major information relay center in the brain receives and processes sensory, motor, limbic and arousal input from various regions of the CNS and relays the information to multiple brain structures including the cerebral cortex.
Notably, decreases in WBV only reached statistical significance from wk 3, indicating that tissue volume decrease in the CTX alone at wk 1 is insufficient to induce a change in WBV in lactacystin-lesioned animals, but that changes in multiple brain structures are required.
Thus, we conclude that genes commonly sex-biased in multiple brain structures are primarily attributed to the sex chromosomes.
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We designed and fabricated a microwire optrode array and a drivable optrode array, which are suitable for targeting single sites in relatively shallow brain structures and multiple sites in relatively deep structures, respectively.
Functional recovery after SCI is a complex phenomenon that is not limited to a single brain structure or intracellular signaling pathways, hence requiring further study aimed at unraveling the underlying interactions between different brain structures and multiple signaling pathways.
Complex cognitive operations such as memory formation and decision-making are thought to be mediated not by single, isolated brain structures but by multiple, connected brain areas.
To achieve simultaneous measurement of multiple cellular events in molecularly defined groups of neurons in vivo, we designed a spectrometer-based fiber photometry system that allows for spectral unmixing of multiple fluorescence signals recorded from deep brain structures in behaving animals.
Although changes in whole brain size necessarily reflect selection acting on one or multiple structures within the brain, particular brain structures may not respond proportionally to changes in whole brain size [3].
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multiple brain tumors
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