That is, genetic correlations between cognitive and learning abilities might be epiphenomenal in the sense that multiple genetically independent brain mechanisms could affect each ability, creating genetic correlations among abilities.
Callahan et al. [ 44] have concluded that MDMA produces structural damage to axonal transport mechanisms in multiple brain regions.
Our approach offers the potential to discovery more reliable and accurate drug targets covering multiple brain diseases with shared molecular mechanisms.
A challenge in using anesthetics to study unconsciousness is stating precise, possible mechanisms of anesthetic-induced brain states, and using an anesthetic which acts at single rather than multiple brain targets to test those mechanism (Rudolph and Antkowiak, 2004; Franks, 2008; Brown et al., 2011).
They believe this suggests that alcoholics rely on greater integration of inputs from multiple brain regions as a compensatory mechanism to support task performance.
Studying multiple brain indices simultaneously helps illuminate the mechanisms and time-course of neural processing underlying concurrent sound segregation and may lead to further development and refinement of physiologically driven models of auditory scene analysis.
Especially, we focused on finding molecular mechanisms common to multiple brain diseases.
Thus, interventions at GlyT1 are highly effective in modifying multiple brain functions, and dissection of their respective mechanisms is expected to further maximize their therapeutic potential for human mental diseases.
A total of 4,307 gene sets were identified to be coexpressed in at least two brain diseases, implying that there might be large number of molecular mechanisms commonly associated to multiple brain diseases with Benjamini corrected p-value of 0.005.
Administration of intranasal oxytocin modulates multiple brain regions during experimental tasks; however, the neural mechanisms that underscore the changes associated with oxytocin administration are yet to be fully elucidated.
The "gene dosage" hypothesis predicts that in DS, overexpression of a single gene can impair multiple brain functions through a signal amplification effect due to impaired regulatory mechanism(s).
