Sentence examples for multiple brain functions from inspiring English sources
Thus, interventions at GlyT1 are highly effective in modifying multiple brain functions, and dissection of their respective mechanisms is expected to further maximize their therapeutic potential for human mental diseases.
The "gene dosage" hypothesis predicts that in DS, overexpression of a single gene can impair multiple brain functions through a signal amplification effect due to impaired regulatory mechanism(s).
Pituitary adenylate cyclase-activating polypeptide (PACAP) is involved in multiple brain functions.
Most of these bridges are also associated with the network connectors identified previously (40/42; 95.24%), suggesting their involvements in the integrity of multiple brain functions.
For example, acetylcholine an important neurotransmitter involved in multiple brain functions, including cognition inhibits proinflammatory activation in both peripheral monocytes and brain microglia and has anti-inflammatory effects.
The first is that the 16p11.2 region comprises a highly active set of genes, which could present a large genetic target and might explain why multiple brain function, and other, phenotypes are associated with this interval.
Since cAMP plays a central role in regulating multiple brain cell functions, it is likely that other additive actions of adenosine A1 and cannabinoid CB1 receptors, besides inhibition of glutamatergic neurotransmission, might occur at the hippocampus, where a promising cumulative neuroprotective action against neurotoxic insults may occur, which deserves future investigation.
Cholinergic neurotransmission and acetylcholinesterase (AChE; a vital functional enzyme in cholinergic neurotransmission) play important roles in multiple advanced brain functions, such as memory, learning, and attention (Hasselmo and Sarter 2011; reviewed by Soreq and Seidman 2001 and by Woolf and Butcher 2011).
Considering the critical role of AMPARs in the central nerve system function and neurobiological diseases, regulation of their dynamical trafficking by S-palmitoylation also serves as a predominant determinant of multiple fundamental brain functions and pathological process.
S-palmitoylation, an important lipid modification by post-translational addition of a long-chain fatty acid to a cysteine residue, regulates AMPA receptor trafficking, which dynamically affects multiple fundamental brain functions, such as learning and memory.
To discover the biological meaning and functions of each gene set from single and multiple brain disease, function enrichment analysis of each gene list was performed using DAVID.
