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Six individuals (graves 20, 34, 130, 161, 184, and 191) are of special interest, but only the skeletal material from grave 130 will be discussed here since it shows lesions on multiple bone elements.
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[Figure 1 Panel D]; IV) multiple bone biopsies (which showed focal necrosis and remodeled lamellar bone tissue with interlamellar spaces occupied by fibrosis and round-oval elements not otherwise specified) were examined by two different and independent pathologists, definitely excluding a malignant disease.
Multiple bone islands are noted.
Only the analysed bone elements are coloured.
Multiple bone metastases relapsed 18 months after the operation.
Duplicate bone elements are right and left, repectively.
Multiple bone and lung metastases were revealed 14 months postoperatively.
In these three cases the description of bone deformities was suggestive of multiple bone localization.
Most patients in the study had bone-only disease (58.2%) and most had multiple bone lesions.
In bone, CXCL-12 is produced by multiple bone marrow cell types, including osteoblasts.
Bone scintigraphy was indicated to outline the polyostotic form and the implication of multiple bone structures.
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