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Much of the progress in the enantioselective C C multiple bond activation catalysed by gold has been achieved in the last few years in intramolecular reactions.
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On the other hand, π back donation has more impact on the activation of the multiple bond.
The interaction of alkenes, acetylene, benzene and acetone with Cu+ sites in Cu-zeolites resulted in the activation of the multiple bond.
An analysis of the shapes adopted by species with multiple bonds suggests that each multiple bond can be treated as a single "superpair" of electrons.
Nitrogen-hydrogen bond activation can be studied by following the reaction NH3 + ND3→ NH2D + NHD2.
Heteronuclear multiple bond connectivity.
Keywords: B3LYP; C Si bond activation; H Si bond activation; Ethylsilane; Co+ cation.
Fig. 5 Heteronuclear multiple bond correlation (HMBC) of DNPH-glucose.
In these cases CH bond activation precedes nucleophilic attack.
The issue of the selectivity in C H bond activation is solved using directing groups.
Hence, the only rate-determining step is the methane dissociation on the metal sites (C H bond activation).
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