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My patient admitted to promiscuity and had received multiple blood transfusions in the early 1980's.
Multiple blood transfusions lead to significant iron overload in these patients.
But this efficacy had come at a cost; the treatment was tough to endure, with intractable vomiting, repeated hospitalisation for infections and multiple blood transfusions.
To report a patient with a large gastrointestinal stromal tumor (GIST) who received multiple blood transfusions intraoperatively and developed a transfusion-related acute lung injury (TRALI).
"She was in dire straits, she needed multiple blood transfusions, and she wound up needing a hysterectomy, which could have been averted if she had been given the appropriate medications," Dr. Tracy said.
Typing serums are obtained from the blood of persons who have rejected grafts or have had multiple blood transfusions or multiple pregnancies; as previously stated, such persons may develop antibodies to transplantation antigens.
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Patients were considered for inclusion in the cohort if they had any risk factor for acute respiratory distress syndrome (ARDS), including sepsis, septic shock, trauma, aspiration, or multiple blood product transfusions.
Coagulopathy developed, bleeding continued through an abdominal drain, and she died 2 days after delivery despite re-laparotomy and multiple blood product transfusions.
Another likely explanation is that a patient's underlying heart condition combined with multiple, rapid blood transfusions lead to pulmonary oedema.
Multiple blood product transfusion was defined as transfusion of ≥6 units consisting of at least 2 units of erythrocytes and 2 units of fresh frozen plasma.
The incidence of the other risk factors, including prior immunosuppressive drugs and severe hypoalbuminemia, abdominal surgical operations, multiple blood product transfusion, parental nutrition and prior antibacterial exposure, did not differ between the two groups.
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