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As both tests were performed on a single and different gastric biopsy and H. pylori infection presents a focal characteristic of infection [ 36], to improve sensitivity of this method, multiple biopsy sampling is recommended.
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Multiple biopsy samples from each patient were stored in paraformaldehyde and embedded en bloc in paraffin.
Multiple biopsy samples were submitted for histologic analysis, culture, and molecular biological analysis.
Moreover, multiple deep injections in tumoral tissue provided better distribution of TEA and allowed multiple biopsy samples to be taken without active bleeding.
When multiple biopsy samples were obtained from the lesion, the patient was considered as positive if at least one sample is positive.
The use of multiple biopsy samples in this time-course study was essential to establish the link between gene expression variation and late-life adiposity.
The stage of transformation that cyclin E deregulation occurs at was investigated using multiple biopsy samples from 13 patients treated at the Umeå University Hospital between 1982 and 2000 for cervical lesions at different stages.
Multiple core biopsy samples obtained under ultrasound or CT guidance were formalin-fixed and embedded in paraffin blocks.
The 24 OPSCC patients provided multiple fresh biopsy samples at the time of diagnostic or therapeutic surgery.
After informed consent, 24 consecutive patients with OPSCC donated multiple fresh biopsy samples (from regions of macroscopically normal and invasive tumor material) at Cambridge University Hospitals National Health Service Foundation Trust between June 2011 and July 2013.
Multiple biopsy overcomes these shortcomings with a single endoscope pass that cuts, like a needle biopsy, up to 25 biopsy samples of uniform size and depth during endoscope withdrawal.
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