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Diabetes care involves monitoring risk factors for both macrovascular and microvascular complications and therefore the sample size needed to detect multiple biologically and clinically relevant effect sizes requires special consideration.
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Endothelial cells produce and secrete multiple biologically active substances that help to maintain normal angiostasis and balance of blood.
However, this process is often further complicated by the potential for multiple biologically functional conformations [ 12], and cases where only a portion of a larger RNA structure is required for biological function.
In rapidly dividing cells GS is required as a precursor for the synthesis of multiple biologically active compounds including purines, pyrimidines, and aminosugars [1].
Furthermore, it has been hypothesized that breast cancer is a complex disease and that variants in multiple biologically related genes combine to affect the risk.
The integration of data from multiple biologically relevant studies facilitates the prioritization of interesting metabolite features and increases the value and reliability of results.
Matrigel contains multiple biologically active molecules, such as laminin, collagen IV and many growth factors [ 15], that are likely to impact the results obtained.
Significant proportion of SNPs (110 of 140: 78.6 %) clustered in ~293 kb region on chromosome 2 (Table 1), which maps to multiple biologically interesting genes (Genes important for cell division and Cancer development) including CFLAR, CLK1, FAM126B, NDUFB3, NIF3L1, ORC2 and PPIL 3 (Table 2; Fig. 1b).
Circulating tumor cells can readily be detected through PCR applications – such approaches appear to be more sensitive than current capture-based techniques – and may be more informative especially because multiple, biologically informative genes identified from RNA analyses can be assessed e.g., in non-small cell lung cancer [ 29], prostate cancer [ 30] or colon cancer [ 31].
The multiple biologically active trace element delivery remains a problem in regeneration medicine and tissue engineering.
We seek to assist such integration by distinguishing among multiple biologically distinct mechanisms by which predator intimidation can affect prey density and, thus, population dynamics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com