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However, biologically a gene or a sample could participate in multiple biological pathways, and a cellular process is generally active only under a subset of genes or experimental conditions.
But, the scientists wrote, "the original hypothesis was overly simplistic because the effects of diet on coronary heart disease can be mediated through multiple biological pathways other than serum total cholesterol or low-density lipoprotein cholesterol".
These genes presumably take part in multiple biological pathways, including glycolysis and regulation of the actin cytoskeleton, and impact various cellular functions, including chemoattractant activity.
The past two decades have seen a remarkable growth in our understanding of sepsis and the complex interconnection of multiple biological pathways involved in the septic process.
They note that it hits only one unproven mechanism behind stroke and that it may be necessary to hit multiple biological pathways to get a significant effect.
Recent success in applications of combinatorial immunotherapy has suggested that targeting multiple biological pathways simultaneously may be critical in treating complex immune pathologies.
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Further analysis showed that they were overrepresented in multiple biological pathway and network ontologies, including inflammatory response (P = 6.3E-6), cell differentiation (P = 1.6E-5), angiogenesis (P = 1.1E-4), and immune system response (P = 2.6E-4).
Pathway and network analyses of these findings implicated multiple interesting biological pathways as well as stimulatory and/or inhibitory relationships among these genes.
Brca1 appears to have a role in multiple complex biological pathways including DNA damage repair, transcriptional regulation, and cell-cycle checkpoint control.
Because of the role of FKBP5 in the regulation of multiple important biological pathways as discussed in this review, variation in FKBP5 could be of significance in many diseases beyond cancer, and in diseases such as diabetes (Tian, 2005).
Interestingly, the molecular signature comprises transporter proteins such as hemopexin, serum albumin and serotransferrin, along with metabolites such as succinate, pantothenate and glutamine, which are involved in multiple complex biological pathways.
More suggestions(15)
various biological pathways
multiple chemical pathways
multiple biological modules
multiple biological redundancies
multiple biological functions
multiple biological scales
multiple biological processes
multiple biological replicates
multiple biological targets
multiple biological samples
multiple possible pathways
multiple biological factors
multiple cellular pathways
multiple biological roles
multiple biological reasons
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