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This study investigates a new paper-based 3D microfluidic analytical device for analyzing multiple biological fluids.
Multiple biological fluids (i.e. human saliva, urine and rat blood and serum) were successfully tested for compatibility with the device and actuation mechanism, demonstrating low slip angles and high contact angles.
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The microdialysis probes were implanted into the jugular vein toward right atrium and the bile duct of Sprague Dawley rats for multiple biological fluid sampling.
Spectroscopic techniques characterise rapidly and simultaneously multiple chemical compounds in biological fluids [10], [19] [28].
These cell arrays were proven to enable rapid (<4 h) and simultaneous analysis of <span class="lh">multiple targets from complex biological fluids [ 33, 36].
Using this array, multiple amino acids in biological fluids were quantitatively determined within 4 h, simply by measuring bioluminescent signals from immobilized cells, without any pre- or posttreatment.
As purified TDH has multiple biological activities, including induction of fluid accumulation in the rabbit intestine, it has been considered a major virulence factor of V. parahaemolyticus [6] [16].
Multiple species of LPA exist in biological fluids and are identified according to the composition of their fatty acid side chain.
An additional key difference is that our study used RA SF as the chemoattractant to assess whether the multiple biological constituents of these disease-related fluids may display differences in chemoattraction between p21 and WT fibroblasts.
Given that MSU crystals preferentially form and deposit on cartilage and are found in biological fluids where there are multiple different proteins and molecules present, it seems likely that MSU nucleation in vivo occurs in a primary heterogeneous manner (induced by foreign particles).
The difficulty is aggravated further by the ambiguous results of the cultures of different biological fluids and by the rapid progression to multiple organ dysfunction [ 1].
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