However, these genes have key roles in multiple cell biological events, and therefore their downregulation in normal cells would have adverse effects on normal cell functioning [18].
This illustrates the complex nature of c-erbB-2 gene disregulation in cancer and suggests that multiple combinations of biological events and consequences are possible.
Network and pathway analyses have also shown that various signaling pathways can interact or even partially overlap with each other, thereby suggesting that IPF may be the result of multiple, consecutive (or interactive) biological events, possibly triggered by environmental stimuli.
One can expect that the multiple, comparative analyses of biological events during the formation of hybrids will ultimately facilitate an inference of the rules and principles that control the fate of duplicated genes and will lead to an enhanced appreciation of the effects of distant hybridization on the formation and the natural evolution of new species.
Multiplexing approaches are advantageous for a variety of reasons including, (1) the ability to undertake combinatorial biological approaches where different reporter readouts allow the association of different biological events, (2) multiple FP readouts can further resolve molecular mechanisms, and (3) data can be quickly acquired from multiple readouts in the same sample.
Child and adult visitors in this study accessed multiple explanatory systems to explain biological events; moreover, they shifted between explanatory frameworks as a consequence of the gallery visit.
Multiple biological macromolecules and physical cell events involve zinc as a structural component or as a major regulator.
It is increasingly recognized that complex diseases such as cancers are a consequence of alterations in a complicated cascade of events involving multiple biological processes and pathways.
Of course, experimentally testing the events and replication on multiple biological samples, from different individuals, will be essential for full validation.
These biological events would lead to multiple assignments of exon orthologs and we can't evade this challenge even it's complicated and increase many efforts in exon orthology construction.
