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Multiple biological consequences of oxidative stress are known to contribute to aging and aging-related pathologies.
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Nuclear translocation and hence the level of Smad signaling into the nucleus is regulated by multiple factors, often with profound biological consequences [ 55].
Long indels that affect multiple amino acids may have significant biological consequences.
These observations indicate that we have made progress in addressing a major challenge in the miRNA field, namely that of interpretation of biological consequences of in vivo multiple miRNA modulation [ 23].
To better understand the biological consequences of simultaneous changes in multiple miRNAs we utilised a weighted score ranking analysis method [ 19], which identifies the protein targets most likely to be regulated by collective changes in miRNA expression.
Multiple target proteins of ISG15 have recently been identified; however, the biological consequences of modification by ISG15 remain to be determined (Hamerman et al, 2002; Malakhov et al, 2003; Giannakopoulos et al, 2005; Zhao et al, 2005).
These variations in cytotoxic response indicate that a more detailed and carefully controlled evaluation of ZnO NP effects on multiple types of normal human cells is needed to better understand the biological consequences of NP exposure.
Despite the multiple and different uses of lecithin with pharmaceutical and therapeutic purposes, the possible biological consequences of phosphatidylcholine administration should be considered.
Given the complicated nature of these two important processes and their interaction, especially the multiple countervailing effects of ROS, a quantitative model is essential to understand the biological consequences.
It is increasingly recognized that complex diseases such as cancers are a consequence of alterations in a complicated cascade of events involving multiple biological processes and pathways.
Obviously this has negative biological consequences.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com