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Next, we will discuss multiple biological barriers to effective drug delivery.
Multiple biological barriers exist for drugs to successfully reach their intended disease sites.
The fundamental problem with in vivo application of gene silencing agents is the lack of effective carriers for systemic delivery in order to overcome the multiple biological barriers [ 13].
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The development of targeted nanotechnology-based drug delivery improves the drug/gene delivery and overcome multiple physiological, physical and biological barriers which are associated with conventional chemotherapy.
102 Nanotechnology offers a wealth of safe tools for the treatment and diagnosis of cardiovascular disease, such as targeted devices with unique therapeutic properties that, because of their small size, can pass biological barriers and deliver multiple therapeutic agents directly to cardiomyocytes.
However, recently the combinatorial use of multiple biological tools appears to have broken the barrier impending clinical development.
But until now, formidable biological barriers have prevented scientists from domesticating the thousands of other fish in the sea.
Niclosamide has multiple biological activities.
Multiple biological factors might participate in REL2 controlled leaf rolling.
These multiple biological activities in the same enzyme occur frequently.
Data included in this review indicate that CNT do not cross biological barriers readily.
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