We simultaneously identified multiple biological warfare agents in environmental samples by looking at specific probe responses after hybridization and response patterns of the multiplexed array.
Early aggressive therapy with multiple DMARDs including biological agents is highly effective in preventing disease progression [19].
Anticancer biological agents have multiple interactions with conventional drugs.
Median survival is now of the order of 20 22 months in patients who receive biological agents and multiple sequential chemotherapy regimes [ 65].
Biological agents have multiple interactions with conventional drugs and, when new drugs are prescribed, the potential for interactions must always be checked.
Median survival following systemic treatment is now of the order of 20 22 months in patients who receive biological agents and multiple sequential chemotherapy regimes, 5-year survival remains close to 0%%.
Previous studies have shown the validity of using claims data to identify serious adverse events associated with biological agents, especially when multiple indicators based on diagnosis codes and inpatient and outpatient treatments were used [ 12, 13].
The EFSA Guidance Document on the risk assessment of plant protection products in bees highlights the need for the inclusion of an uncertainty analysis, other routes of exposures and multiple stressors such as chemical mixtures and biological agents.
In fact, the design of single agents that act against multiple biological targets is of increasing interest and prominence.
