In addition, our study found a strong association between head circumference, a measure of brain development that is also strongly associated with fetal growth and school age cognitive performance, after adjustment for multiple concurrent home, environment and biologic factors.
IRFs, a family of nine mammalian transcription factors, have multiple biologic functions that when dysregulated may contribute to tumorigenesis; most well-known are their roles in regulating/initiating host immunity.
Upon activation, JNK induces multiple biologic events through the transcription factor activator protein-1 and transcription-independent control of effector molecules.
However, it is likely that the multiple biologic activities of this agent were critical to its success in PROWESS.
Highly specific binding of 1α,25-dihydroxyvitamin D3 (1α,25(OH)2D3) by vitamin D receptor (VDR), a nuclear transcriptional factor, activates a genomic mechanism that is manifested in the multiple biologic properties of 1α,25(OH)2D3.
Proteins with changed concentrations contributed to multiple biologic pathways relevant to the observed clinical effects of HT, including coagulation, inflammation, immune response, metabolism, cell adhesion, growth factors, and osteogenesis.
Syntenin is a scaffolding-PDZ domain-containing protein involved in multiple biologic functions, including syndecan binding and recycling, receptor clustering, protein trafficking, signal transduction, and regulation of the transcription factor Sox4 proteasomal degradation [ 2- 7].
aPTT is frequently impacted by biologic factors.
Subject 3 had the most number of previous treatments including multiple systemic treatments and multiple biologic therapies.
Such cLBP is often termed nonspecific and may be due to multiple biologic and behavioral etiologies.
