The final functional outcome of this cascade of intracellular events is the induction of the multiple biologic effects of the PI3K/AKT/mTOR signaling pathway.
Among the multiple biologic pathways in which NHERF1 is involved, the signaling event that is most relevant to NHERF1 pathobiology in mammary gland is not known, nor is it certain that NHERF1 elicits tumour suppressor activity in breast.
Recent trials designed to assess atherosclerosis risk in the community have suggested that evaluation of multiple biologic markers may not only risk stratify diabetic patients, but also give information about the pathogenesis of cardiovascular events (CVEs).
Subject 3 had the most number of previous treatments including multiple systemic treatments and multiple biologic therapies.
Such cLBP is often termed nonspecific and may be due to multiple biologic and behavioral etiologies.
Molecular imaging involves the noninvasive real-time observation of in vivo biologic events at the molecular level.
The critical role of hedgehog signaling in multiple biologic processes raises concerns about its potential therapeutic use in cancer.
The design of probes for molecular imaging target two basic classes of biologic events, including alteration in metabolic processes and changes in receptor expression.
Although Cox-2 is generally associated with biologic events such as injury, inflammation, and proliferation [29], the knockout mouse model surprisingly shows abnormal kidney development.
Our exhaustive analysis of gene expression in MM, compared to normal pleural samples, confirm the complexity of biologic events responsible of neoplastic transformation.
