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However, it is likely that the multiple biologic activities of this agent were critical to its success in PROWESS.
However, because of the multiple biologic activities of these compounds, the mechanism of their antitumor activity and its relation to HPA inhibition are not straightforward.
Collectively, these observations suggest that FRAT1 may play a pivotal role in the development and progression of gliomas due to its multiple biologic activities involved in promoting proliferation, invasion, and angiogenesis.
Therefore, the multiple biologic activities of phytoestrogens raise the question of whether they have the potential to influence the outcome and/or interpretation of bioassays used to identify chemicals with estrogenic potential.
IL-6 is a pleiotropic cytokine with multiple biologic activities (Van Snick 1990) that has been shown to be up-regulated after silica (Hetland et al. 2001) and asbestos (Simeonova et al. 1997) exposure of human lung epithelial cells.
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Niclosamide has multiple biological activities.
Normal human serum IgG is comprised of multiple glycoforms and biologic activities, other than catabolism, varies between glycoforms.
Biologic activities of functional mediators activate downstream transducers regulating inflammation and carcinogenesis.
Subject 3 had the most number of previous treatments including multiple systemic treatments and multiple biologic therapies.
Such cLBP is often termed nonspecific and may be due to multiple biologic and behavioral etiologies.
The natural product tetramethylpyrazine (TMP) has a variety of biologic activities, including neuroprotection.
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multiple biologic replicates
multiple biologic programs
multiple biologic processes
multiple biologic therapies
multiple biologic data
multiple biologic properties
multiple biologic markers
multiple biologic systems
multiple research activities
multiple biologic factors
multiple biologic effects
multiple enzyme activities
multiple biologic pathways
multiple biologic events
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