Exact(1)
The system integrates, for each predicted gene, the results of multiple bioinformatics methods (Blast result on UniProt and specialized genomic data, InterPro, COG, PRIAM, synteny group computation using the complete bacterial genomes available at NCBI RefSeq, etc; more information on the syntaxic and functional annotation process is given in [ 78]).
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This strategy was effective and efficient for phylogenetic inference, subtyping, and routine investigation of serotype Enteritidis, especially when multiple instruments, library preparation, and bioinformatics methods are available for whole-genome SNP typing applications in public health laboratories.
There is already considerable research in progress toward applying parallel computing techniques on bioinformatics methods, such as multiple sequence alignment, gene expression analysis and phylogenetic studies.
Performing such comprehensive network analysis requires systematic bioinformatics methods to integrate multiple genomic datasets.
Identification of combinations of transcriptional regulatory elements from large amounts of DNA sequences can benefit greatly from proposed bioinformatics methods as the multiple alignments and the LGM.
Bioinformatics methods can be used to identify an integrated panel of multiple physiological networks and biomarkers.
D.M. devised bioinformatics methods, carried out data analysis and wrote the paper.
In Bioinformatics methods and protocols (eds Misener, S. & Krawetz, S. A.) Ch. 20, 365 386 (Springer, 1999).
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