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Multiple bioinformatics infrastructures have been established to compile data derived from these techniques.
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Unfortunately, bioinformatics infrastructures for this relatively young discipline are limited only to some specialists.
Both versions can be downloaded as local installations or as Amazon Cloud images which makes TREAT available for users with no access to local bioinformatics infrastructures.
'DAS' (Distributed Annotation System; Prlić et al., 2007) and 'BioMoby' (Wilkinson and Links, 2002) are web-based, service-oriented bioinformatics infrastructures, enabling interoperability across distributed resources.
We also thank IIT Madras and the Bioinformatics Infrastructure Facility, supported by the DBT, Govt of India, for infrastructural support.
"It is the biggest dollop of money ever put into [European] bioinformatics infrastructure".
The de.NBI (German network for bioinformatics infrastructure) service center in Dortmund provides several software applications and platforms as services to meet these demands.
Based on the functional requirements of the Resource Center, we developed a bioinformatics infrastructure for integration of PRC deliverables (Figure 1).
Further integration of genetic, functional, and structural insights about the molecular basis of tumorigenesis into robust bioinformatics infrastructure can ultimately help to discover molecular signatures of cancer mutations.
A detailed description of the multiple bioinformatic analyses used in this report is provided in Supplementary Methods S1.
We also thank the Swedish Bioinformatics Infrastructure for Life Sciences BILSS).
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