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New drug regimens may consist of multiple biologically active agents designed to act synergistically on multiple biochemical targets.
The propolis extract present a multitude of constituents that can act on multiple biochemical targets affecting the balance of complex cellular networks in a way that is currently not fully understood such as the multi target efficacy model proposed by CSERMELY et al. [2].
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New therapeutic strategies comprise drug candidates designed specifically to act on multiple neural and biochemical targets for the treatment of cognition impairment, motor dysfunction, depression and neurodegeneration.
Curcumin is known to target multiple biochemical pathways, such as those mediated by Wnt/β-catenin [ 26], NF-κB [ 20], growth factor receptors like EGFR and HER2 [ 27], and JAK/STAT [ 28] enhancing its effect on cancer cells.
These common strain effects suggest the possibility of common modifier(s) across multiple biochemical modalities and thus potential targets of broad therapeutic appeal.
Its breakdown involves multiple biochemical reactions.
Multiple biochemical assays were employed for substrate validation.
Exercise induces multiple biochemical changes that may affect gene expression [43, 44].
This overexpression also leads to multiple biochemical and physiological changes associated with chilling stress.
braziliensis through different biochemical targets such as cytoplasmic membrane and the mitochondrial respiratory complex.
Vo-Dinh and coworkers have developed nanobiosensors to detect biochemical targets inside living single cells [5 12].
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