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Multiple biochemical assays were employed for substrate validation.
We have performed multiple biochemical assays which indicate this modification is ubiquitin (Figure 4C and D).
Multiple biochemical assays have been utilized to support the discovery of small-molecule inhibitors of epigenetic enzymes, but the development of cellular binding assays for protein protein interactions involving the so-called 'reader' domains has lagged behind.
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Liu et al. explored multiple regions of this quinazoline scaffold and discovered UNC0224 (2) in 2009, which was significantly more potent than BIX01294 in multiple biochemical and biophysical assays.
Statistics among multiple groups on cell proliferations and biochemical assays were carried out using one-way ANOVA test to determine significant differences.
Apicomplexan parasites, including Babesia, Theileria, Toxoplasma, and Cryptosporidium spp. generally are not easy to manipulate experimentally as many have complex life cycles within multiple hosts and it may be difficult to obtain sufficient quantities of parasites for biochemical assays.
Cell-based screening approaches offer some advantages in the quest for novel inhibitors because they can include multiple targets in a single screen and in some cases reveal targets and/or structures not captured in biochemical assays.
The results were confirmed with biochemical assays and the testimony of family members.
All biochemical assays were run in triplicate.
This was demonstrated by clinical examination and biochemical assays.
Filters used to extract compounds from Biochemical assays.
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