Sentence examples for multiple binding modules from inspiring English sources

Several studies have shown that the tethering of multiple binding modules can enhance RNA-binding affinity and specificity, a strategy also commonly used in DNA recognition.

ESCRT-0, containing proteins with multiple Ub-binding modules, is the primary sensor for ubiquitinated membrane proteins.

On the other hand, the GIY-YIG domains in HEases are inherently non-specific and require fusions with multiple DNA-binding modules [ 31] to recognize their long targets.

If the IREs function as composite binding modules for multiple transcription factors, then the chicken IRE-like element might contain a subset of the binding modules found in mammalian IREs as well as distinct modules.

Thus, the C-terminus of H1 may encompass interaction module(s) for multiple binding partners of linker histone H1.

Such enzymes may contain single or multiple catalytic modules (GH) together with single or multiple noncatalytic carbohydrate-binding modules (CBMs) [ 10].

cis-Regulatory modules (CRMs) of eukaryotic genes often contain multiple binding sites for transcription factors.

Cis-regulatory modules (CRMs, also called enhancers) are approximately 1-kb long sequences that typically harbor multiple binding sites for one or more TFs and mediate the combinatorial influence of those TFs on gene expression (Davidson 2010).

Most notably, in developmental genes, multiple binding sites of different TFs are often located close to each other in genomes, forming so called cis-regulatory modules (CRMs), and work together to generate precise expression patterns [2].

To integrate multiple signals present on distal sites within the same tail or on separate histones, many nuclear proteins harbor several binding modules, or multiply their interaction capabilities through oligomerization.

Many different zinc binding modules have been identified.