Sentence examples for multiple base lesions from inspiring English sources

Joined repair mechanisms are not mutually exclusive due to the complex processing of lesions such as interstrand crosslink [7] or multiple base lesions that can be processed through subpathways for NHEJ [8], and can be species-specific.

In addition, closely located multiple base and/or sugar modifications as well as strand breaks, forming so-called clustered lesions, can be refractory to excision by DNA glycosylases [12], [13], [14].

DNA base lesion analysis.

Patients with severe disease had multiple lesions, multiple debridements, or multiple skin grafts.

Multiple-base substitutions at or near the lesion were detected at a frequency of 1−3%.

Multiple lesions (more than two lesions) were detected in six patients (40%).

T[5-Me,8]G induced a higher frequency of targeted base substitutions than G[8,5-Me]T did, but both lesions caused a wide variety of mutations at or near the cross-link, including single- and multiple-base substitutions as well as small frameshifts.

DNA base-lesion levels in splenic tissue.

Based on the occurrence of severe or multiple (≥3) lesions in young patients, AS changes can be distinguished from degenerative changes with a high reliability [18].

"He has multiple lesions in multiple parts of the body," Koller said.

Our method is based on the detailed noise distribution derived from of test-retest data and accounts for multiple target lesions in a rigorous statistical manner.